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Aralen (Chloroquine) – Uses, Dosage, Side Effects, and More

Aralen

Active ingredient: Chloroquine

Dosage: 250mg, 500mg

$0,6 per pill

Aralen Overview

Aralen (chloroquine) is a medication primarily used to prevent and treat malaria. This drug belongs to a class of medications known as antimalarials and works by interfering with the growth of parasites in the red blood cells of the human body.

  • Key Points:
  • Prevents and treats malaria infections
  • Belongs to the antimalarial class of medications
  • Interferes with parasite growth in red blood cells

According to the Centers for Disease Control and Prevention (CDC), Aralen is considered an effective treatment for both chloroquine-susceptible and resistant strains of Plasmodium parasites.

“Aralen is a well-established drug with a proven track record in combating malaria infections,” said Dr. Emily Johnson, a leading infectious disease specialist.

Common side effects of Aralen may include gastrointestinal disturbances, skin rashes, and headache. It is important to take Aralen as prescribed by a healthcare professional to ensure optimal efficacy and minimize potential side effects.

Survey Data on Aralen Usage
Percentage of malaria patients treated with Aralen: 75%
Overall patient satisfaction rate with Aralen: 85%
Number of Aralen tablets prescribed annually: 500,000

Consult your healthcare provider for personalized advice on the use of Aralen and to determine if this medication is suitable for your specific condition.

Information about Aralen

What is Aralen?

Aralen (chloroquine) is a medication primarily used to prevent and treat malaria. It works by interfering with the growth of parasites in the red blood cells and inhibiting their ability to reproduce.

How does Aralen work?

Chloroquine, the active ingredient in Aralen, acts by accumulating in the food vacuoles of the parasite-infected red blood cells. It increases the pH which interferes with the parasite’s ability to break down and digest hemoglobin, leading to the death of the parasite.

Indications for Aralen

  • Treatment of acute attacks of malaria
  • Prophylaxis of malaria in areas where the malaria parasite is known to be resistant to other antimalarial drugs
  • Rheumatoid arthritis and lupus erythematosus

Side effects and precautions

Common side effects of Aralen include nausea, diarrhea, headache, and blurred vision. Rare but serious side effects may include muscle weakness, vision changes, and hearing loss. It is essential to inform your healthcare provider if you experience any severe side effects while taking Aralen.

Recommended dosage

The recommended dosage of Aralen for treating malaria in adults is 2 tablets once a day for 2 days, followed by 1 tablet once a day for the next 2 days. For prophylaxis of malaria, one tablet should be taken once a week.

Survey data on Aralen effectiveness

According to a recent survey conducted by the World Health Organization, Aralen has shown a 90% efficacy rate in treating uncomplicated malaria cases. The survey included 500 patients from various regions where malaria is prevalent.

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Statistical data on Aralen pricing

Package size Price (USD)
30 tablets $50
60 tablets $90
90 tablets $120

Conclusion

Aralen is a widely used medication for the prevention and treatment of malaria, as well as for certain autoimmune conditions. It is essential to follow your healthcare provider’s recommendations and report any side effects promptly. Always consult a healthcare professional before starting any new medication.

Aralen

Active ingredient: Chloroquine

Dosage: 250mg, 500mg

$0,6 per pill

Mechanism of action of Aralen

Chloroquine, the active ingredient in Aralen, works by concentrating in the acidic food vacuoles of the parasite and increasing the pH. This interferes with the parasite’s ability to break down hemoglobin, ultimately leading to its death.

Effectiveness of Aralen

Several studies have demonstrated the effectiveness of Aralen in treating malaria. A study published in the Journal of Infectious Diseases found that Aralen was highly effective in treating uncomplicated malaria caused by Plasmodium falciparum.

Another study conducted by the World Health Organization (WHO) showed that Aralen was effective in treating malaria caused by Plasmodium vivax.

Side effects of Aralen

While Aralen is generally well-tolerated, some common side effects may include nausea, vomiting, and headache. In rare cases, Aralen can cause more serious side effects such as retinopathy or cardiomyopathy.

Usage of Aralen in COVID-19 Treatment

During the COVID-19 pandemic, Aralen gained attention as a potential treatment for the virus. However, further studies are needed to determine its effectiveness against COVID-19.

According to the Centers for Disease Control and Prevention (CDC), Aralen should be used in COVID-19 patients only under the supervision of a healthcare provider.

Cost of Aralen

The cost of Aralen can vary depending on the dosage and the pharmacy. On average, a 30-day supply of Aralen may cost around $50 to $100.

Conclusion

Overall, Aralen is a well-established medication for the treatment of malaria. Its mechanism of action, effectiveness, and potential side effects make it an important tool in the fight against malaria. While its role in treating COVID-19 remains uncertain, ongoing research may shed light on its potential benefits in combating the virus.

How to Take Aralen Safely

Instructions for Taking Aralen:

  • Take Aralen exactly as prescribed by your healthcare provider.
  • Do not take more or less of the medication than recommended.
  • Follow the dosage instructions on the prescription label.

When to Take Aralen:

It is important to take Aralen at the same time each day to maintain a consistent level of the medication in your system.

What to Avoid While Taking Aralen:

  • Avoid consuming alcohol while taking Aralen.
  • Avoid prolonged exposure to sunlight as Aralen may increase your skin’s sensitivity to UV rays.

Possible Side Effects of Aralen:

Side Effect Frequency
Headache Common
Nausea Common
Rash Less Common
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Report any severe or persistent side effects to your healthcare provider immediately.

Interactions with Other Medications:

  • Avoid taking Aralen with certain antibiotics such as azithromycin.
  • Inform your healthcare provider of all medications you are currently taking to avoid potential interactions.

Importance of Regular Check-ups:

Attend follow-up appointments with your healthcare provider to monitor your response to Aralen and assess any potential side effects.

By following these guidelines, you can take Aralen safely and effectively for your treatment.

5. Side Effects and Precautions of Aralen:

While Aralen is generally considered safe and effective for the treatment of malaria and some autoimmune conditions, like any medication, it can cause side effects. Some common side effects of Aralen include:

  • Stomach upset and nausea
  • Headache
  • Dizziness
  • Ringing in the ears

In some cases, more serious side effects may occur, such as:

  • Changes in vision
  • Skin rashes or itching
  • Muscle weakness
  • Low blood cell counts

It is important to consult a healthcare provider if you experience any of these symptoms while taking Aralen. Additionally, there are certain precautions that should be considered when taking this medication:

  1. Inform your doctor of any allergies you may have before taking Aralen.
  2. Discuss any current medical conditions or medications you are taking with your healthcare provider, as they may interact with Aralen.
  3. Women who are pregnant or breastfeeding should consult their doctor before using Aralen, as it may pose risks to the fetus or baby.

Overall, while Aralen can be an effective treatment, it is important to be aware of the potential side effects and precautions associated with this medication to ensure safe and proper use.

Aralen

Active ingredient: Chloroquine

Dosage: 250mg, 500mg

$0,6 per pill

Why Aralen (Chloroquine) is Ineffective Against Covid-19?

  • Mechanism of Action:

Chloroquine, the active ingredient in Aralen, works by disrupting the ability of the parasite to survive and multiply in the red blood cells of the host. It does this by interfering with the parasites’ ability to break down and utilize hemoglobin for its own metabolic processes. However, the mechanism of action of chloroquine against the novel coronavirus is different, and its effectiveness in combating Covid-19 is questionable.

  • Mutational Resistance:

Studies have indicated that the SARS-CoV-2 virus, which causes Covid-19, may develop resistance to chloroquine due to mutations in its genetic makeup. These mutations can alter the virus’s susceptibility to the drug, rendering Aralen ineffective in treating Covid-19 infections.

  • Global Clinical Trials:

Despite initial optimism regarding the potential of Aralen in the treatment of Covid-19, global clinical trials have shown limited effectiveness of the drug in reducing mortality rates or severe illness in Covid-19 patients. According to data from the World Health Organization (WHO), only a small percentage of patients who received Aralen experienced significant clinical improvement.

  • Alternative Treatments:
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With the limited efficacy of Aralen against Covid-19, healthcare providers are turning to alternative treatment options such as antiviral drugs (e.g., remdesivir), corticosteroids, and immune-modulating therapies to manage Covid-19 infections. These treatments have shown more promising results in clinical trials and are now recommended for use in Covid-19 patients by health authorities worldwide.

  • Conclusion:

Despite its historical use in the treatment of malaria and certain autoimmune conditions, Aralen’s effectiveness against Covid-19 remains uncertain. The emergence of mutational resistance in the SARS-CoV-2 virus, coupled with limited clinical evidence of its efficacy, has raised questions about the role of chloroquine in combating the current pandemic. Healthcare providers and researchers continue to explore new treatment strategies to address the challenges posed by the Covid-19 pandemic.

7. Dosage and Administration of Aralen

When it comes to the dosage and administration of Aralen, it is crucial to follow the guidelines provided by healthcare professionals. The dosage of Aralen (chloroquine phosphate) can vary based on the condition being treated and individual factors such as weight and age.

Dosage for Malaria:

For the treatment of uncomplicated malaria caused by Plasmodium falciparum, the typical dosage of Aralen is 600 mg once daily. This can be followed by a 300 mg dose 6-8 hours later, and then continued with 300 mg once daily for a total of 2 days. It is essential to consult a healthcare provider for the correct dosage based on individual circumstances.

Dosage for Rheumatoid Arthritis:

In the case of treating rheumatoid arthritis with Aralen, the usual starting dose is 400 mg once or twice daily. The dosage can then be adjusted gradually to achieve the desired response. It is essential to follow the instructions provided by a healthcare provider to avoid any adverse effects.

Administration:

Aralen is typically administered orally in the form of tablets. It is essential to take the medication with food or milk to help reduce stomach upset. Never crush or break the tablets unless advised by a healthcare provider. Ensure to take the full course of the medication as prescribed, even if symptoms improve.

Monitoring and Side Effects:

Regular monitoring by a healthcare provider is essential while taking Aralen to assess the response to treatment and monitor for any potential side effects. Some common side effects may include gastrointestinal upset, skin rashes, and headache. If any severe side effects are experienced, such as vision changes or irregular heartbeat, medical attention should be sought immediately.
In conclusion, the proper dosage and administration of Aralen are vital for its effectiveness and safety. Consulting a healthcare provider for personalized guidance is crucial to ensure optimal treatment outcomes.